A hormone-free pill, called YCT-529, that temporarily stops sperm production by blocking a vitamin A metabolite has just concluded its first safety trial in humans, getting a step closer to increasing male contraceptive options
    • oce 🐆@jlai.luOPEnglish
      0·
      7 months ago

      Could it be the first one to pass this test phase?

      To study the safety of YCT-529 in humans, we conducted a Phase 1a clinical trial where 16 healthy men received either placebo or escalating single doses of YCT-529 to assess its safety and tolerability. YCT-529 was well tolerated, and no adverse effects were noted. The positive results from this first clinical trial laid the groundwork for a second trial, where men receive YCT-529 for 28 days and 90 days, to study safety and changes in sperm parameters.

    • I_Fart_Glitter@lemmy.worldEnglish
      0·
      7 months ago

      Female birth control has to be safer and have fewer side effects than pregnancy.

      Male birth control has to be safer and have fewer side effects than letting women carry the burden of birth control.

      There will not be a male birth control pill. We would be better off putting these resources toward improving the safety of female birth control.

        • I_Fart_Glitter@lemmy.worldEnglish
          0·
          7 months ago

          It is a bit callous. I’m old enough to have seen this pop up a dozen or so times.

          Every time the depression, weight gain, acne and libido changes are deemed too severe for approval and women are sitting here like… yeah, it’s all that plus increased occurrence of stroke and heart attack for us, but ok.