• SnausagesinaBlanket@lemmy.world
    link
    fedilink
    arrow-up
    101
    ·
    19 hours ago

    How the Therapy Works

    The process involves regenerative medicine, utilizing the patient’s own body’s capabilities to treat the illness.

    Cell Extraction:A small sample of cells (e.g., fat cells or blood cells) is taken from the patient. Reprogramming: These cells are chemically treated in a lab to revert them to a pluripotent state, meaning they can develop into any type of cell.

    Differentiation and Transplantation: The stem cells are then guided to become functional, insulin-producing islet cells. These new cells are then transplanted back into the patient’s abdominal area.

    Restored Function: Once implanted, the cells engraft and begin producing insulin naturally in response to blood glucose levels, effectively restoring the body’s natural ability to regulate blood sugar.

    • FoxyFerengi@startrek.website
      link
      fedilink
      arrow-up
      24
      ·
      17 hours ago

      That doesn’t make sense for type 2. This is exactly how they’ve been trialing treatment of type 1, they just announced it a few months ago I think it was Stanford and Toronto

      • SaveTheTuaHawk@lemmy.ca
        link
        fedilink
        English
        arrow-up
        1
        ·
        4 hours ago

        Insulin producing cells die off in type 2 after years of being bombarded with sugar in the US diet.

    • lectricleopard@lemmy.world
      link
      fedilink
      arrow-up
      19
      arrow-down
      1
      ·
      19 hours ago

      I wonder if the US diabetic population is comparable to the Chinese diabetic population. Similar weight and eating habits? If not that could complicate things.

      • Leather@lemmy.world
        link
        fedilink
        arrow-up
        4
        ·
        5 hours ago

        I believe you may conflating type 1, and type 2. Type 1 does not have a causal relationship with food consumption. The article also might be conflating the two as it mentions curing type 2, but by using the methodology everyone has been looking into to treat the autoimmune issues of type 1s.

      • UnderpantsWeevil@lemmy.world
        link
        fedilink
        English
        arrow-up
        36
        ·
        18 hours ago

        Rate of diabetes in China “explosive”

        China has the world’s largest diabetes population, with over 118 million adults (approx. 11–12% prevalence) living with the disease as of late 2024–2025, driven by rapid urbanization, obesity, and an aging population. The epidemic has shifted dramatically from less than 1% prevalence in 1980 to a major public health challenge, with type 2 diabetes accounting for over 90% of cases

        This is a consistent pattern in Chinese domestic politics. What a western nation would pick out as a profit center, the Chinese state addresses as a social cost. So the state plows a small fortune into cost-effective medical solutions, rather than squeezing the existing health care system out for therapeutic remedies that never resolve the root problem.

        • protist@mander.xyz
          link
          fedilink
          English
          arrow-up
          9
          arrow-down
          2
          ·
          17 hours ago

          This is a consistent pattern in Chinese domestic politics

          What are other examples?

          It should be noted that this treatment sounds likely to be very expensive, and also if someone doesn’t change their lifestyle, the newly implanted functional cells are likely to become dysfunctional again over time, requiring another expensive cycle of treatment

          • UnderpantsWeevil@lemmy.world
            link
            fedilink
            English
            arrow-up
            10
            ·
            14 hours ago

            What are other examples?

            Environmental policy was a big one. China took a hard pivot in the '00s, cutting emissions, advancing alternative energy, reforesting deserts, rapidly advancing HSR, building enormous wild life refugees.

            Their insourcing of processors was another. Going from Taiwan’s biggest customer to it’s biggest competitor in a decade and change.

            Then there was the housing boom - remember “Chinese Ghost Towns”? All over the news in the early '10s. Now China has more homeowners than any other county on Earth with more than 90% of households owning at least one property.

            • Swedneck@discuss.tchncs.de
              link
              fedilink
              arrow-up
              2
              ·
              5 hours ago

              i’ve never understood how anyone could think the “ghost towns” wouldn’t obviously be filled shortly. One of the most significant facts about China is that they have a stupendously massive population, and consider Boston a quaint medium-sized town.

          • chaogomu@lemmy.world
            link
            fedilink
            English
            arrow-up
            4
            ·
            14 hours ago

            This isn’t a cure for type 2, it’s a cure for type 1. Lifestyle has very little effect on type 1. You just don’t have enough insulin, sometimes you don’t have any, and usually it’s a result of an autoimmune disease or genetic issue.

            • protist@mander.xyz
              link
              fedilink
              English
              arrow-up
              5
              ·
              14 hours ago

              In the actual study, the subject had Type 2 diabetes, and the authors note that treating Type 1 will be much more difficult due to the immunology involved

              • Leather@lemmy.world
                link
                fedilink
                arrow-up
                2
                ·
                4 hours ago

                Agreed, the article says all of this but it doesn’t make a lot of sense. This is generally the mindset everyone has been using to treat type 1. Type 1 is about production, type 2 is about resistance. This treatment doesn’t address resistance, it just makes more insulin. More insulin is not more better, and has consequences.

              • chaogomu@lemmy.world
                link
                fedilink
                English
                arrow-up
                2
                ·
                13 hours ago

                I’m sorry, I just assumed that cancer of a site got it wrong, and then went on to assume it was another example where someone had and autoimmune disease, and then had their immune system reset via something like chemo. The pancreas in such cases is still roached, so adding new insulin producing cells makes sense.

                Type 2 is caused by insulin resistance. And yeah, more insulin can help, but I’d not call it a cure. A cure is reversing the resistance.

      • SaveTheTuaHawk@lemmy.ca
        link
        fedilink
        English
        arrow-up
        2
        ·
        4 hours ago

        This was one test in one patient. We didn’t hear about the patients where this didn’t work. Very shitty article.